Let A=A(α,β) be a graded down-up algebra with (degx,degy)=(1,n) and β≠0, and let ∇A be the Beilinson algebra of A. If n=1, then a description of the Hochschild cohomology group of ∇A is known. In this paper, we calculate the Hochschild cohomology group of ∇A for the case n≥2. As an application, we see that the structure of the bounded derived category of the noncommutative projective scheme of A is different depending on whether (10) (α1β0)n(10) is zero or not. Moreover, it turns out that there is a difference between the cases n=2 and n≥3 in the context of Grothendieck groups.