Let Z4 be the ring of integers modulo 4. We study the Λ-constacyclic and (θ,Λ)-cyclic codes over the non-chain ring R=Z4[u,v]/⟨u2=1,v2=0,uv=vu=0⟩ for a unit Λ=1+2u+2v in R. We define several Gray maps and find that the respective Gray images of a quasi-cyclic code over Z4 are cyclic, quasi-cyclic or permutation equivalent to this code. For an odd positive integer n, we determine the generator polynomials of cyclic and Λ-constacyclic codes of length n over R. Further, we prove that a (θ,Λ)-cyclic code of length n is a Λ-constacyclic code if n is odd, and a Λ-quasi-twisted code if n is even. A few examples are also incorporated, in which two parameters are new and one is best known to date.