In this paper, we introduce the concept of Baer (p,q)-sets. Using this notion, we define Rickart, Baer, quasi-Baer and π-Baer (S,R)-bimodules, respectively. We show how these conditions relate to each other. We also develop new properties of the minus binary relation, ≤-, we extend the relation ≤- to (S,R)-bimodules and use it to characterize the aforementioned Rickart, Baer, quasi-Baer, and π-Baer (S,R)-bimodules. Moreover, we specify subsets 𝒦 of the power set of a (S,R)-bimodule for which ≤- determines a partial order and for which ≤- is a lattice. We analyze the relation ≤- by examining the associated Baer (p,q)-sets. Finally, we apply our results to C∗-modules. Examples are provided to illustrate and delimit our results.