Let the curvature of a plane curve parametrized by arclength s be given as a function of the Cartesian co-ordinates of the points the curve is passing through in the Euclidean plane. Then, the co-ordinates of its position vector are determined by a system of equations arising from the Frenet-Serret relations that can be regarded as a dynamical system of two degrees of freedom determining the motion (trajectories) of a particle of unit mass, s playing the role of time. Here, two classes of integrable systems of the foregoing type are identified. For that purpose, we explore the variational symmetries of a generic system of this kind with respect to Lie groups of point transformations of the involved variables. As a result, a set of sufficient conditions are found which ensure that such a system possesses two functionally independent integrals of motion and, consecutively, is integrable by quadratures. In each such case, we achieve either an explicit parameterization of the corresponding trajectory curves in terms of their curvatures or, at least, a separation of the dependent variables.