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The internal force calculation of the raft foundation of high- and low-rise buildings is complicated, and it is affected by many different factors. Consequently, it does not have a uniform calculation method. The internal force change rules for the thick raft foundation must be obtained to consider the effects of the soil, foundation, and complex high-rise building interactions through a large-scale model test. When the raft flexure is less than 0.2‰, the internal force is calculated by a simple local bending moment method. The control index of raft flexure is 0.5‰, which is useful to the designer.