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This book is conceptualised from a successful course in recent years on cellular biophysics as part of the Masters program in Biophysics at the University of Barcelona. It develops a physical approach to biological processes that aims at a quantitative understanding of fundamental mechanisms and organizational principles behind biological complexity. The focus is on the mechanical aspects at different scales, from molecular force generation to collective cell migration, all treated in a comprehensive and unified manner.
It is also self-contained and presents the basic concepts from physics and biology that may complement the different backgrounds of potential students. Whenever possible, the presentation is illustrated with simple quantitative models and many of the examples found are solved explicitly. A collection of additional problems and exercises is also included.
Contents:
- Preface
- Introduction
- Basic Concepts from Physics
- Basic Concepts from Biology
- Mechanics of Cell Membranes
- Molecular Force Generation and Active Transport
- Rheology and Fluctuations of Biological Materials
- Hydrodynamics of Active Polar Gels
- Cell Motility by Swimming
- Actin-Based Cell Motility
- Mechanics of Growing Tissues
- Appendices:
- Derivation of the Oseen Tensor
- Stochastic Processes
- Aspects of Complexity in Soft Matter
- Mechanics of Continuum Media
- Hydrodynamics of Nematic Liquid Crystals
Readership: Graduate students and reasearchers in biophysics.
