These proceedings review the current state of knowledge of the induction of cancer in humans by internally deposited radionuclides. The topics considered in this seminar will be broadened to include radionuclides other than radium and thorium, such as polonium, plutonium, americium, and strontium. More emphasis will be given to creating a bridge between epidemiology, molecular biology, cancer genetics and low-dose effects.
This seminar provides new perspectives for future research in the health effects of internally deposited radionuclides and opens doors for closer international cooperation.
Contents:
- Internal Dosimetry Schemes — Their Physical, Biological, and Epidemiological Basis (K Eckerman)
- Biokinetic Models and Data (A Kaul)
- The Distribution of Thorotrast in the Bone Marrow: A Study Using Human and Monkey Tissues (N D Priest et al.)
- Dose-Response Relationships for Female Radium Dial Workers: A New Look (R E Rowland)
- The Role of Laboratory Animals in Studying the Late-Occurring Effects of Radionuclides Deposited in the Liver and Skeleton (B B Boecker et al.)
- The Implications of a Two-Mutation Carcinogenesis Model for Internal Emitters (K H Chadwick et al.)
- Cancer and Genes: The Paradigm of the Pediatric Cancer Neuroblastoma (M Schwab)
- Molecular Biology of Carcinogenesis: The Unstable Genome (H Höfler et al.)
- The Use of Epidemiological and Experimental Data in Assessing Health Effects from Internally Deposited Radionuclides (J W Stather)
- and other papers
Readership: Medical professionals, nuclear medicine scientists and radiologists.
