Bone Structure and Remodeling

This volume aims at bringing together investigators from a number of sub-fields to attempt an integrative approach. Thus, the mechanical aspects of bone are studied by anatomists, biologists, clinicians and engineers. In each case, individual investigators usually have some knowledge of the other fields, but disciplinary allegiances mean that it is remarkably difficult to get them all together in one group. The process of diffusion across disciplines represented in this volume will strengthen and hopefully be the start of the development of a coherent theory concerning bone structure and remodelling. The chapters include theoretical, mechanical, architectural and experimental approaches. They especially attempt to elucidate the complexities involved in the different methodologies and the interactions amongst the different disciplines.

• Bone Structure and Remodeling: An Introduction (H Weinans & A Odgaard)
• The Law of Adaptive Bone Remodeling: A Case for Crying Newton? (R Huiskes)
• Bone Remodeling and Its Consequences for Bone Structure (E F Eriksen & B Langdahl)
• Response of Isolated Osteocytes to Mechanical Loading in Vitro (J Klein-Nulend et al.)
• Endogeneous Control of Bone Morphology via Frequency Specific, Low Magnitude Functional Strain (C T Rubin & K J McLeod)
• The Mechanism of Bone Adaptation: Tension and Resorption in the Human Incus (C Oxnard et al.)
• The Role of Trabecular Architecture in the Anisotropic Mechanical Properties of Bone (B van Rietbergen et al.)
• Material Properties of Single Osteons and Osteonic Lamellae Using High Frequency Scanning Acoustic Microscopy (J L Katz & A Meunier)
• Mathematical Modeling of Microdamage in Bone Remodeling and Adaptation (P J Prendergast & R Huiskes)
• Comparing an Optimal Global Efficiency Assumption to a Principal Stress-based Formulation for the Simulation of Anisotropic Bone Adaptation to Mechanical Loading (C R Jacobs et al.)
• Modeling Diaphyseal Changes during Growth and Adaptation (M C H van der Meulen et al.)
• Stable Adaptation of Bone Apparent Density (D P Fyhrie et al.)
• and other papers